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Introducing cost effective and easy molecular diagnostic methods is recommended, implementing molecular diagnostic methods in research areas and intensive training of personnel in the use of equipment.Zoonotic tuberculosis; Molecular techniques; Africa; AFS: Acid Fast Stain; AIDS: Acquired Immune Deficiency Virus; BCG: Bacillus Calmette–Guérin; BTB: Bovine Tuberculosis; CBPP: Contagious Bovine Pleuropnemonia; DNA: Deoxyribonucleic Acid; DRE: Double Repetitive Element; DST: Drug Susceptibility Test; ETR: Exact Tandem Repeats; FAFLP: Fluorescent Amplified Fragmented Length Polymorphism; Flip: Fast Ligation Mediates; GC: Gas Chromatography; HIV: Human Immune Deficiency Virus; LAM: Lipoarabinomannan; LF: Lateral Flow; LM: Ligation Mediated; LPA: Line Probe Assay; MIRU: Mycobacterial Interspersed Repetitive Unit; MTC: Mycobacterium tuberculosis Complex; OIE: World Organization for Animal Health (Office International des Epizooties); PCR: Polymerase Chain Reaction; PFGE: Pulsed-Field Gel Electrophoresis; PGRS: Polymorphic GC-Rich Sequences; PLHIV: People Living With HIV; QUB: Queen’s University Belfast; RFLP: Restriction Fragment Length Polymorphism; RIF: Rifampin; SNP: Single Nucleotide Polymorphism; TB: Tuberculosis; VNTR: Variable Number Tandem Repeat; WHO: World Health Organization The worldwide in 2015, there were an estimated 10.4 million new TB cases worldwide.Globally, an estimated 1.8 million people died of TB in 2015, at least 3 people per minute, of whom 0.4 million were co-infected with HIV.Although the number of TB deaths fell by 22% between 20, TB remained 1 of the top 10 causes of death worldwide in 2015, responsible for more deaths than HIV and malaria, the WHO says.Animal TB is widely distributed in many developing countries.

This needs to accelerate to a 4% to 5% annual decline by 2020 to reach the first milestones of the End TB Strategy, the WHO notes.

; contribute to a lesser extent, which is mostly acquired from domestic animals and their products, in which cattle are the major reservoir [1].

The disease also causes serious threat in endangering wildlife species.

It can be said that the bovine TB control program in developing country is null [2].

Studies indicates for example in most African countries, bovine TB is prevalent, but effective disease control including regular milk pasteurization and slaughterhouse meat inspection, is largely absent.

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